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Targeting translational read-through of premature termination mutations in BMPR2 with PTC124 for pulmonary arterial hypertension

Pulmonary arterial hypertension is a fatal disorder of the lung circulation in which accumulation of vascular cells progressively obliterates the pulmonary arterioles. This results in sustained elevation in pulmonary artery pressure leading eventually to right heart failure. Approximately, 80% of fa...

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Detalhes bibliográficos
Publicado no:Pulm Circ
Main Authors: Long, Lu, Yang, Xudong, Southwood, Mark, Moore, Stephen, Crosby, Alexi, Upton, Paul D., Dunmore, Benjamin J., Morrell, Nicholas W.
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7372630/
https://ncbi.nlm.nih.gov/pubmed/32733669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2045894020935783
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