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High-Throughput Analysis of Fluorescently Labeled N-Glycans Derived from Biotherapeutics Using an Automated LC-MS-Based Solution

Protein glycosylation can impact the efficacy and safety of biotherapeutics and therefore needs to be well characterized and monitored throughout the drug product life cycle. Glycosylation is commonly assessed by fluorescent labeling of released glycans, which provides comprehensive information of t...

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Bibliographische Detailangaben
Veröffentlicht in:SLAS Technol
Hauptverfasser: Zhang, Ximo, Reed, Corey E., Birdsall, Robert E., Yu, Ying Qing, Chen, Weibin
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE Publications 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7372583/
https://ncbi.nlm.nih.gov/pubmed/32458729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2472630320922803
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