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High-Throughput Analysis of Fluorescently Labeled N-Glycans Derived from Biotherapeutics Using an Automated LC-MS-Based Solution

Protein glycosylation can impact the efficacy and safety of biotherapeutics and therefore needs to be well characterized and monitored throughout the drug product life cycle. Glycosylation is commonly assessed by fluorescent labeling of released glycans, which provides comprehensive information of t...

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Detalhes bibliográficos
Publicado no:SLAS Technol
Main Authors: Zhang, Ximo, Reed, Corey E., Birdsall, Robert E., Yu, Ying Qing, Chen, Weibin
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7372583/
https://ncbi.nlm.nih.gov/pubmed/32458729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2472630320922803
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