Efficient miRNA Inhibitor with GO-PEI Nanosheets for Osteosarcoma Suppression by Targeting PTEN

BACKGROUND: Gene therapy is considered a novel way to treat osteosarcoma, and microRNAs are potential therapeutic targets for osteosarcoma. miR-214 has been found to promote osteosarcoma aggression and metastasis. Graphene oxide (GO) is widely used for gene delivery for the distinct physiochemical p...

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Опубликовано в: :Int J Nanomedicine
Главные авторы: Ou, Lingling, Lin, Haiyingjie, Song, Yuwei, Tan, Guoqiang, Gui, Xiujuan, Li, Jinyuan, Chen, Xiaoting, Deng, Zhendong, Lin, Shaoqiang
Формат: Artigo
Язык:Inglês
Опубликовано: Dove 2020
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Original Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7372002/
https://ncbi.nlm.nih.gov/pubmed/32764941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S257084
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