Modulation of MnSOD and FoxM1 Is Involved in Invasion and EMT Suppression by Isovitexin in Hepatocellular Carcinoma Cells

BACKGROUND: Manganese superoxide dismutase (MnSOD) induces FoxM1 expression, subsequently contributing to migration in several cancer cells. Isovitexin (ISOV) was recently found to downregulate MnSOD and FoxM1, decreasing stemness in hepatocellular carcinoma (HCC) stem-like cells (HCSLCs). The curre...

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Bibliographische Detailangaben
Veröffentlicht in:Cancer Manag Res
Hauptverfasser: Qiu, Yebei, Cao, Xiaocheng, Liu, Lihua, Cao, Xiaozheng, Yuan, Qing, Li, Xiang, Cui, Yinghong, Xu, Chang, Zou, Chang, Ren, Kaiqun, Cao, Jianguo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove 2020
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7371559/
https://ncbi.nlm.nih.gov/pubmed/32765079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S245283
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