Isovitexin reduces carcinogenicity and stemness in hepatic carcinoma stem-like cells by modulating MnSOD and FoxM1

BACKGROUND: Manganese superoxide dismutase (MnSOD) upregulating FoxM1 have previously been demonstrated promoting lung cancer stemness. Isovitexin exhibits antitumor activities in various cancers. This study aimed to assess whether isovitexin inhibits hepatic carcinoma stem-like cells (HCSLCs) featu...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Exp Clin Cancer Res
Auteurs principaux: Cao, Xiaocheng, Liu, Lihua, Yuan, Qing, Li, Xiang, Cui, Yinghong, Ren, Kaiqun, Zou, Chang, Chen, A., Xu, Chang, Qiu, Yebei, Quan, Meifang, Zhang, Jiansong, Cao, Jianguo, Chen, Xiangding
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2019
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6580799/
https://ncbi.nlm.nih.gov/pubmed/31208440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1244-6
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