MEIS-mediated suppression of human prostate cancer growth and metastasis through HOXB13-dependent regulation of proteoglycans

The molecular roles of HOX transcriptional activity in human prostate epithelial cells remain unclear, impeding the implementation of new treatment strategies for cancer prevention and therapy. MEIS proteins are transcription factors that bind and direct HOX protein activity. MEIS proteins are putat...

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Publicat a:eLife
Autors principals: VanOpstall, Calvin, Perike, Srikanth, Brechka, Hannah, Gillard, Marc, Lamperis, Sophia, Zhu, Baizhen, Brown, Ryan, Bhanvadia, Raj, Vander Griend, Donald J
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2020
Matèries:
Cancer Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7371429/
https://ncbi.nlm.nih.gov/pubmed/32553107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.53600
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