Novel C-4 Heteroaryl 13-cis-Retinamide Mnk/AR Degrading Agents Inhibit Cell Proliferation and Migration and Induce Apoptosis in Human Breast and Prostate Cancer Cells and Suppress Growth of MDA-MB-231 Human Breast and CWR22Rv1 Human Prostate Tumor Xenografts in Mice

Lignende værker

• Simultaneous targeting of androgen receptor (AR) and MAPK-interacting kinases (MNKs) by novel retinamides inhibits growth of human prostate cancer cell lines
  af: Ramamurthy, Vidya P., et al.
  Udgivet: (2014)
• The retinamide VNLG-152 inhibits f-AR/AR-V7 and MNK–eIF4E signaling pathways to suppress EMT and castration-resistant prostate cancer xenograft growth
  af: Ramamurthy, Vidya P., et al.
  Udgivet: (2018)
• Targeting of protein translation as a new treatment paradigm for prostate cancer
  af: Ramamurthy, Vidya P., et al.
  Udgivet: (2017)
• First Mnks degrading agents block phosphorylation of eIF4E, induce apoptosis, inhibit cell growth, migration and invasion in triple negative and Her2-overexpressing breast cancer cell lines
  af: Ramalingam, Senthilmurugan, et al.
  Udgivet: (2014)
• Galeterone and VNPT55 disrupt Mnk-eIF4E to inhibit prostate cancer cell migration and invasion
  af: Kwegyir-Afful, Andrew K., et al.
  Udgivet: (2016)