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Galeterone and VNPT55 disrupt Mnk-eIF4E to inhibit prostate cancer cell migration and invasion

Metastatic castration-resistant prostate cancer (mCRPC) accounts for a high percentage of prostate cancer mortality. The proprietary compound galeterone (gal) was designed to inhibit proliferation of androgen/androgen receptor (AR)-dependent prostate cancer cell in vitro and in vivo and is currently...

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Detalhes bibliográficos
Publicado no:FEBS J
Main Authors: Kwegyir-Afful, Andrew K., Bruno, Robert D., Purushottamachar, Puranik, Murigi, Francis N., Njar, Vincent C. O.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5118139/
https://ncbi.nlm.nih.gov/pubmed/27618366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.13895
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