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Identification of Novel Steroidal Androgen Receptor Degrading Agents Inspired by Galeterone 3β-Imidazole Carbamate

[Image: see text] Degradation of all forms of androgen receptors (ARs) is emerging as an advantageous therapeutic paradigm for the effective treatment of prostate cancer. In continuation of our program to identify and develop improved efficacious novel small-molecule agents designed to disrupt AR si...

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Detalhes bibliográficos
Publicado no:ACS Med Chem Lett
Main Authors: Purushottamachar, Puranik, Kwegyir-Afful, Andrew K., Martin, Marlena S., Ramamurthy, Vidya P., Ramalingam, Senthilmurugan, Njar, Vincent C. O.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2016
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4948004/
https://ncbi.nlm.nih.gov/pubmed/27437082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.6b00137
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