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Concentration-response evaluation of ToxCast compounds for multivariate activity patterns of neural network function

The US Environmental Protection Agency’s ToxCast program has generated toxicity data for thousands of chemicals but does not adequately assess potential neurotoxicity. Networks of neurons grown on microelectrode arrays (MEAs) offer an efficient approach to screen compounds for neuroactivity and dist...

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Vydáno v:Arch Toxicol
Hlavní autoři: Kosnik, Marissa B., Strickland, Jenna D., Marvel, Skylar W., Wallis, Dylan J., Wallace, Kathleen, Richard, Ann M., Reif, David M., Shafer, Timothy J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7371233/
https://ncbi.nlm.nih.gov/pubmed/31822930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-019-02636-x
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