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Concentration-response evaluation of ToxCast compounds for multivariate activity patterns of neural network function

The US Environmental Protection Agency’s ToxCast program has generated toxicity data for thousands of chemicals but does not adequately assess potential neurotoxicity. Networks of neurons grown on microelectrode arrays (MEAs) offer an efficient approach to screen compounds for neuroactivity and dist...

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Detalles Bibliográficos
Publicado en:Arch Toxicol
Main Authors: Kosnik, Marissa B., Strickland, Jenna D., Marvel, Skylar W., Wallis, Dylan J., Wallace, Kathleen, Richard, Ann M., Reif, David M., Shafer, Timothy J.
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7371233/
https://ncbi.nlm.nih.gov/pubmed/31822930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-019-02636-x
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