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Influenza A viruses use multivalent sialic acid clusters for cell binding and receptor activation
Influenza A virus (IAV) binds its host cell using the major viral surface protein hemagglutinin (HA). HA recognizes sialic acid, a plasma membrane glycan that functions as the specific primary attachment factor (AF). Since sialic acid alone cannot fulfill a signaling function, the virus needs to act...
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| Publicado no: | PLoS Pathog |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7371231/ https://ncbi.nlm.nih.gov/pubmed/32639985 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008656 |
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