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Monocyte Chemoattractant Protein-1 (MCP-1), Not MCP-3, Is the Primary Chemokine Required for Monocyte Recruitment in Mouse Peritonitis Induced with Thioglycollate or Zymosan A

MCP-1/CCL2 plays a critical role in monocyte recruitment into sites of immune responses and cancer. However, the role of other MCPs remains unclear. In this study, we generated a novel MCP-1-deficient (designated as MCP-1(Δ/Δ)) mouse model by deleting a 2.3-kb DNA fragment from the mouse genome usin...

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Détails bibliographiques
Publié dans:J Immunol
Auteurs principaux: Takahashi, Munehisa, Galligan, Carole, Tessarollo, Lino, Yoshimura, Teizo
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7371094/
https://ncbi.nlm.nih.gov/pubmed/19641140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0802812
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