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Inhibition of miR-181a promotes midbrain neuronal growth through a Smad1/5-dependent mechanism: implications for Parkinson’s disease

Parkinson’s disease (PD) is the second most common neurodegenerative disease, and is characterized by the progressive degeneration of nigrostriatal dopaminergic (DA) neurons. Current PD treatments are symptomatic, wear off over time and do not protect against DA neuronal loss. Finding a way to re-gr...

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Detalhes bibliográficos
Publicado no:Neuronal Signal
Main Authors: Hegarty, Shane V., Sullivan, Aideen M., O’Keeffe, Gerard W.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7371012/
https://ncbi.nlm.nih.gov/pubmed/32714583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/NS20170181
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