Inhibiting the Activity of NADPH Oxidase in Cancer

Significance: The primary function of NADPH oxidases (NOX1–5 and dual oxidases DUOX1/2) is to produce reactive oxygen species (ROS). If inadequately regulated, NOX-associated ROS can promote oxidative stress, aberrant signaling, and genomic instability. Correspondingly, NOX isoforms are known to be...

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Vydáno v:Antioxid Redox Signal
Hlavní autoři: Konaté, Mariam M., Antony, Smitha, Doroshow, James H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc., publishers 2020
Témata:
NOX Inhibitors (Ed. Hervé Kovacic)—Part B
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7370979/
https://ncbi.nlm.nih.gov/pubmed/32008376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2020.8046
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