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Single-cell analysis of human embryos reveals diverse patterns of aneuploidy and mosaicism
Less than half of human zygotes survive to birth, primarily due to aneuploidies of meiotic or mitotic origin. Mitotic errors generate chromosomal mosaicism, defined by multiple cell lineages with distinct chromosome complements. The incidence and impacts of mosaicism in human embryos remain controve...
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| Veröffentlicht in: | Genome Res |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7370883/ https://ncbi.nlm.nih.gov/pubmed/32641298 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.262774.120 |
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