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Meningioma cells express primary cilia but do not transduce ciliary Hedgehog signals

Meningiomas are the most common primary intracranial tumors, but treatment options for meningioma patients are limited due to incomplete understanding of tumor biology. A small percentage of meningiomas harbor somatic variants in the Hedgehog pathway, a conserved gene expression program that is esse...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Findakly, Sarah, Choudhury, Abrar, Daggubati, Vikas, Pekmezci, Melike, Lang, Ursula E., Raleigh, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7370519/
https://ncbi.nlm.nih.gov/pubmed/32690089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-020-00994-7
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