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Differential contribution of p300 and CBP to regulatory element acetylation in mESCs

BACKGROUND: The transcription coactivators CREB binding protein (CBP) and p300 are highly homologous acetyltransferases that mediate histone 3 lysine 27 acetylation (H3K27ac) at regulatory elements such as enhancers and promoters. Although in most cases, CBP and p300 are considered to be functionall...

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Bibliografische gegevens
Gepubliceerd in:BMC Mol Cell Biol
Hoofdauteurs: Martire, Sara, Nguyen, Jennifer, Sundaresan, Aishwarya, Banaszynski, Laura A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7370441/
https://ncbi.nlm.nih.gov/pubmed/32690000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12860-020-00296-9
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