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Deleting key autophagy elongation proteins induces acquirement of tumor-associated phenotypes via ISG15
Autophagy is a cellular catabolic process that maintains intracellular homeostasis using lysosomal degradation systems. We demonstrate that inhibiting autophagy by depleting essential autophagy elongation proteins, Atg5 or Atg7, induces ISG15 expression through STING-mediated cytosolic dsDNA respons...
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| Publicado no: | Cell Death Differ |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7370226/ https://ncbi.nlm.nih.gov/pubmed/32127658 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-0519-y |
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