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Fenretinide induces a new form of dynamin-dependent cell death in pediatric sarcoma

Alveolar rhabdomyosarcoma (aRMS) is a highly malicious childhood malignancy characterized by specific chromosomal translocations mostly encoding the oncogenic transcription factor PAX3-FOXO1 and therefore also referred to as fusion-positive RMS (FP-RMS). Previously, we have identified fenretinide (r...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Brack, Eva, Wachtel, Marco, Wolf, Anja, Kaech, Andres, Ziegler, Urs, Schäfer, Beat W.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7370225/
https://ncbi.nlm.nih.gov/pubmed/32144381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-0518-z
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