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Squamous differentiation requires G2/mitosis slippage to avoid apoptosis
The cellular mechanisms controlling cell fate in self-renewal tissues remain unclear. Cell cycle failure often leads to an apoptosis anti-oncogenic response. We have inactivated Cdk1 or Polo-like-1 kinases, essential targets of the mitotic checkpoints, in the epithelia of skin and oral mucosa. Here,...
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| Publicado no: | Cell Death Differ |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7370216/ https://ncbi.nlm.nih.gov/pubmed/32080348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-0515-2 |
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