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Nintedanib Reduces Neutrophil Chemotaxis via Activating GRK2 in Bleomycin-Induced Pulmonary Fibrosis

Neutrophils are involved in the alveolitis of idiopathic pulmonary fibrosis (IPF). However, their pathogenic mechanisms are still poorly understood. Nintedanib has antifibrotic and anti-inflammatory activity in IPF. This study aimed to investigate the regulatory mechanism of nintedanib on neutrophil...

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Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Chen, Wei-Chih, Chen, Nien-Jung, Chen, Hsin-Pai, Yu, Wen-Kuang, Su, Vincent Yi-Fong, Chen, Hao, Wu, Huai-Hsuan, Yang, Kuang-Yao
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7370174/
https://ncbi.nlm.nih.gov/pubmed/32630825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21134735
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