Small Molecule Enhancers of Endosome-to-Cytosol Import Augment Anti-tumor Immunity

Cross-presentation of antigens by dendritic cells (DCs) is critical for initiation of anti-tumor immune responses. Yet, key steps involved in trafficking of antigens taken up by DCs remain incompletely understood. Here, we screen 700 US Food and Drug Administration (FDA)-approved drugs and identify...

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Udgivet i:Cell Rep
Main Authors: Kozik, Patrycja, Gros, Marine, Itzhak, Daniel N., Joannas, Leonel, Heurtebise-Chrétien, Sandrine, Krawczyk, Patrycja A., Rodríguez-Silvestre, Pablo, Alloatti, Andrés, Magalhaes, Joao Gamelas, Del Nery, Elaine, Borner, Georg H.H., Amigorena, Sebastian
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7370168/
https://ncbi.nlm.nih.gov/pubmed/32668257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.107905
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