Critical role for Sec22b-dependent antigen cross-presentation in antitumor immunity

CD8(+) T cells mediate antigen-specific immune responses that can induce rejection of solid tumors. In this process, dendritic cells (DCs) are thought to take up tumor antigens, which are processed into peptides and loaded onto MHC-I molecules, a process called “cross-presentation.” Neither the actu...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Alloatti, Andrés, Rookhuizen, Derek C., Joannas, Leonel, Carpier, Jean-Marie, Iborra, Salvador, Magalhaes, Joao G., Yatim, Nader, Kozik, Patrycja, Sancho, David, Albert, Matthew L., Amigorena, Sebastian
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5551575/
https://ncbi.nlm.nih.gov/pubmed/28663435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20170229
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