Hypoxia Promotes Prostate Cancer Aggressiveness by Upregulating EMT-Activator Zeb1 and SK3 Channel Expression

Hypoxia is a well-established feature of prostate cancer (PCa) and is associated with disease aggressiveness. The hypoxic microenvironment initiates multiple adaptive responses including epithelial-to-mesenchymal transition (EMT) and a remodeling of calcium homeostasis involved in cancer progression...

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Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Bery, Fanny, Figiel, Sandy, Kouba, Sana, Fontaine, Delphine, Guéguinou, Maxime, Potier-Cartereau, Marie, Vandier, Christophe, Guibon, Roseline, Bruyère, Franck, Fromont, Gaëlle, Mahéo, Karine
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Communication
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7369999/
https://ncbi.nlm.nih.gov/pubmed/32640738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21134786
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