The Differential Effect of Carbon Dots on Gene Expression and DNA Methylation of Human Embryonic Lung Fibroblasts as a Function of Surface Charge and Dose

This study presents a toxicological evaluation of two types of carbon dots (CD), similar in size (<10 nm) but differing in surface charge. Whole-genome mRNA and miRNA expression (RNAseq), as well as gene-specific DNA methylation changes, were analyzed in human embryonic lung fibroblasts (HEL 1246...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Sima, Michal, Vrbova, Kristyna, Zavodna, Tana, Honkova, Katerina, Chvojkova, Irena, Ambroz, Antonin, Klema, Jiri, Rossnerova, Andrea, Polakova, Katerina, Malina, Tomas, Belza, Jan, Topinka, Jan, Rossner, Pavel
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7369946/
https://ncbi.nlm.nih.gov/pubmed/32635498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21134763
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge