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Nonsense Suppression Therapy: New Hypothesis for the Treatment of Inherited Bone Marrow Failure Syndromes

Inherited bone marrow failure syndromes (IBMFS) are a group of cancer-prone genetic diseases characterized by hypocellular bone marrow with impairment in one or more hematopoietic lineages. The pathogenesis of IBMFS involves mutations in several genes which encode for proteins involved in DNA repair...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Bezzerri, Valentino, Api, Martina, Allegri, Marisole, Fabrizzi, Benedetta, Corey, Seth J., Cipolli, Marco
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7369780/
https://ncbi.nlm.nih.gov/pubmed/32630050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21134672
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