Picropodophyllotoxin, an Epimer of Podophyllotoxin, Causes Apoptosis of Human Esophageal Squamous Cell Carcinoma Cells Through ROS-Mediated JNK/P38 MAPK Pathways

Esophageal squamous cell carcinoma (ESCC), a major histologic type of esophageal cancer, is one of the frequent causes of cancer-related death worldwide. Picropodophyllotoxin (PPT) is the main component of Podophyllum hexandrum root with antitumor activity via apoptosis-mediated mechanisms in severa...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Kwak, Ah-Won, Yoon, Goo, Lee, Mee-Hyun, Cho, Seung-Sik, Shim, Jung-Hyun, Chae, Jung-Il
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7369713/
https://ncbi.nlm.nih.gov/pubmed/32629820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21134640
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