Licochalcone D Induces ROS-Dependent Apoptosis in Gefitinib-Sensitive or Resistant Lung Cancer Cells by Targeting EGFR and MET

Licochalcone D (LCD), a flavonoid isolated from a Chinese medicinal plant Glycyrrhiza inflata, has a variety of pharmacological activities. However, the anti-cancer effects of LCD on non-small cell lung cancer (NSCLC) have not been investigated yet. The amplification of MET (hepatocyte growth factor...

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Bibliographic Details
Published in:Biomolecules
Main Authors: Oh, Ha-Na, Lee, Mee-Hyun, Kim, Eunae, Kwak, Ah-Won, Yoon, Goo, Cho, Seung-Sik, Liu, Kangdong, Chae, Jung-Il, Shim, Jung-Hyun
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072161/
https://ncbi.nlm.nih.gov/pubmed/32070026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10020297
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