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Aged Mice Exhibit Severe Exacerbations of Dry Eye Disease with an Amplified Memory Th17 Cell Response
The prevalence as well as the severity of dry eye disease increase with age. Memory T helper 17 (Th17) cells (CD4(+)IL-17A(+)CD44(+)) drive the chronic and relapsing course of dry eye disease. Here, we investigated the contribution of memory Th17 cells to age-related dry eye disease, and evaluated m...
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| Veröffentlicht in: | Am J Pathol |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Investigative Pathology
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7369573/ https://ncbi.nlm.nih.gov/pubmed/32289288 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2020.03.016 |
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