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Mice lacking the purinergic receptor P2X5 exhibit defective inflammasome activation and early susceptibility to Listeria monocytogenes
P2X5 is a member of the P2X purinergic receptor family of ligand-gated cation channels, and has recently been shown to regulate inflammatory bone loss. Here, we report that P2X5 is a protective immune regulator during Listeria monocytogenes (Lm) infection, as P2X5-deficient mice exhibit increased ba...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7369244/ https://ncbi.nlm.nih.gov/pubmed/32540996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1901423 |
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