The purinergic receptor P2X5 regulates inflammasome activity and hyper-multinucleation of murine osteoclasts

Excessive bone resorption by osteoclasts (OCs) can result in serious clinical outcomes, including bone loss that may weaken skeletal or periodontal strength. Proper bone homeostasis and skeletal strength are maintained by balancing OC function with the bone-forming function of osteoblasts. Unfortuna...

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Vydáno v:Sci Rep
Hlavní autoři: Kim, Hyunsoo, Walsh, Matthew C., Takegahara, Noriko, Middleton, Sarah A., Shin, Hong-In, Kim, Junhyong, Choi, Yongwon
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5427844/
https://ncbi.nlm.nih.gov/pubmed/28298636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00139-2
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