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Targeting Lymph Node Niches Enhances Type 1 Immune Responses to Immunization

Generating robust CD4(+) T-helper cell type 1 (Th1) responses is essential for protective vaccine-induced type 1 immunity. Here, we examine whether immunization formulation associated with enhanced vaccine efficacy promotes antigen targeting and cell recruitment into lymph node (LN) niches associate...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Lian, Jeffrey, Ozga, Aleksandra J., Sokol, Caroline L., Luster, Andrew D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7369031/
https://ncbi.nlm.nih.gov/pubmed/32460031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.107679
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