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The chemokine receptor CCR8 promotes the migration of dendritic cells into the lymph node parenchyma to initiate the allergic immune response.
The migration of mature dendritic cells (DC) into the draining lymph node (dLN) is thought to depend solely on the chemokine receptor CCR7. CD301b(+) DCs migrate into the dLN after cutaneous allergen exposure and are required for T helper 2 (Th2) differentiation. We found that CD301b(+) DCs poorly u...
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| Опубликовано в: : | Immunity |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6192021/ https://ncbi.nlm.nih.gov/pubmed/30170811 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2018.07.012 |
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