A new sex-specific underlying mechanism for female schizophrenia: accelerated skewed X chromosome inactivation

BACKGROUND: X chromosome inactivation (XCI) is the mechanism by which the X-linked gene dosage is adjusted between the sexes. Evidence shows that many sex-specific diseases have their basis in X chromosome biology. While female schizophrenia patients often have a delayed age of disease onset and cli...

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Dades bibliogràfiques
Publicat a:Biol Sex Differ
Autors principals: Zhang, Xinzhu, Li, Yuhong, Ma, Lei, Zhang, Guofu, Liu, Min, Wang, Chuanyue, Zheng, Yi, Li, Rena
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7368719/
https://ncbi.nlm.nih.gov/pubmed/32680558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13293-020-00315-6
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