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The application of histone deacetylases inhibitors in glioblastoma

The epigenetic abnormality is generally accepted as the key to cancer initiation. Epigenetics that ensure the somatic inheritance of differentiated state is defined as a crucial factor influencing malignant phenotype without altering genotype. Histone modification is one such alteration playing an e...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Chen, Rui, Zhang, Mengxian, Zhou, Yangmei, Guo, Wenjing, Yi, Ming, Zhang, Ziyan, Ding, Yanpeng, Wang, Yali
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7368699/
https://ncbi.nlm.nih.gov/pubmed/32682428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-020-01643-6
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