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The application of histone deacetylases inhibitors in glioblastoma

The epigenetic abnormality is generally accepted as the key to cancer initiation. Epigenetics that ensure the somatic inheritance of differentiated state is defined as a crucial factor influencing malignant phenotype without altering genotype. Histone modification is one such alteration playing an e...

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Bibliografske podrobnosti
izdano v:J Exp Clin Cancer Res
Main Authors: Chen, Rui, Zhang, Mengxian, Zhou, Yangmei, Guo, Wenjing, Yi, Ming, Zhang, Ziyan, Ding, Yanpeng, Wang, Yali
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7368699/
https://ncbi.nlm.nih.gov/pubmed/32682428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-020-01643-6
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