Loss of the IL-27R Results in Enhanced Tubulointerstitial Fibrosis Associated with Elevated Th17 Responses

Clinical and experimental studies have established that immune cells such as alternatively activated (M2) macrophages and Th17 cells play a role in the progression of chronic kidney disease (CKD), but the endogenous pathways that limit these processes are not well understood. The cytokine IL-27 has...

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Bibliografske podrobnosti
izdano v:J Immunol
Main Authors: Coppock, Gaia M, Aronson, Lillian R, Park, Jihwan, Qiu, Chengxiang, Park, Jeongho, DeLong, Jonathan H., Radaelli, Enrico, Suszták, Katalin, Hunter, Christopher A
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7368461/
https://ncbi.nlm.nih.gov/pubmed/32522836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1901463
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