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Ribosome profiling reveals a functional role for autophagy in mRNA translational control

Autophagy promotes protein degradation, and therefore has been proposed to maintain amino acid pools to sustain protein synthesis during metabolic stress. To date, how autophagy influences the protein synthesis landscape in mammalian cells remains unclear. Here, we utilize ribosome profiling to deli...

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Detalhes bibliográficos
Publicado no:Commun Biol
Main Authors: Goldsmith, Juliet, Marsh, Timothy, Asthana, Saurabh, Leidal, Andrew M., Suresh, Deepthisri, Olshen, Adam, Debnath, Jayanta
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7367890/
https://ncbi.nlm.nih.gov/pubmed/32681145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-1090-2
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