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Itraconazole inhibits the Hedgehog signaling pathway thereby inducing autophagy-mediated apoptosis of colon cancer cells

Itraconazole is as an antifungal medication used to treat systemic fungal infections. Recently, it has been reported to be effective in suppressing tumor growth by inhibiting the Hedgehog signaling pathway and angiogenesis. In the present study, we investigated whether itraconazole induces autophagy...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Deng, Huiming, Huang, Ling, Liao, Zhongkai, Liu, Mi, Li, Qiang, Xu, Ronghua
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7367825/
https://ncbi.nlm.nih.gov/pubmed/32681018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-02742-0
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