Whole-Exome Sequencing Analysis of the Progression from Non-Low Grade Ductal Carcinoma In Situ to Invasive Ductal Carcinoma

PURPOSE: Ductal carcinoma in situ (DCIS) is a non-obligate precursor of invasive breast cancer. Here, we sought to investigate the level of intra-lesion genetic heterogeneity in DCIS and the patterns of clonal architecture changes in the progression from DCIS to invasive disease. DESIGN: Synchronous...

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Publicat a:Clin Cancer Res
Autors principals: Pareja, Fresia, Brown, David N., Lee, Ju Youn, Da Cruz Paula, Arnaud, Selenica, Pier, Bi, Rui, Geyer, Felipe C., Gazzo, Andrea, da Silva, Edaise M., Vahdatinia, Mahsa, Stylianou, Anthe, Ferrando, Lorenzo, Wen, Hannah Y., Hicks, James B., Weigelt, Britta, Reis-Filho, Jorge S.
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7367727/
https://ncbi.nlm.nih.gov/pubmed/32220886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-19-2563
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