A 15-gene immune, stromal and proliferation gene signature that significantly associates with poor survival in patients with pancreatic ductal adenocarcinoma

PURPOSE: Pancreatic ductal adenocarcinoma (PDAC) is a lethal disease with dismal survival rates. Tumor microenvironment (TME), comprising of immune cells and cancer-associated fibroblasts, plays a key role in driving poor prognosis and resistance to chemotherapy. Herein, we aimed to identify a TME-a...

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Vydáno v:Clin Cancer Res
Hlavní autoři: Kandimalla, Raju, Tomihara, Hideo, Banwait, Jasjit K, Yamamura, Kensuke, Singh, Gagandeep, Baba, Hideo, Goel, Ajay
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7367725/
https://ncbi.nlm.nih.gov/pubmed/32234757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-19-4044
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