Serine‐227 in the N‐terminal kinase domain of RSK2 is a potential therapeutic target for mantle cell lymphoma

RSK2 is a serine/threonine kinase downstream signaling mediator in the RAS/ERK signaling pathway and may be a therapeutic target in mantle cell lymphoma (MCL), an almost incurable disease subtype of non‐Hodgkin lymphoma. In this study, serine‐227 (RSK2(Ser227)) in the N‐terminal kinase domain (NTKD)...

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Bibliografske podrobnosti
izdano v:Cancer Med
Main Authors: Matsumura‐Kimoto, Yayoi, Tsukamoto, Taku, Shimura, Yuji, Chinen, Yoshiaki, Tanba, Kazuna, Kuwahara‐Ota, Saeko, Fujibayashi, Yuto, Nishiyama, Daichi, Isa, Reiko, Yamaguchi, Junko, Kawaji‐Kanayama, Yuka, Kobayashi, Tsutomu, Horiike, Shigeo, Taniwaki, Masafumi, Kuroda, Junya
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2020
Teme:
Cancer Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7367644/
https://ncbi.nlm.nih.gov/pubmed/32420699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.3136
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