Aberrant BUB1 Overexpression Promotes Mitotic Segregation Errors and Chromosomal Instability in Multiple Myeloma

Chromosome instability (CIN), the hallmarks of cancer, reflects ongoing chromosomal changes caused by chromosome segregation errors and results in whole chromosomal or segmental aneuploidy. In multiple myeloma (MM), CIN contributes to the acquisition of tumor heterogeneity, and thereby, to disease p...

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Vydáno v:Cancers (Basel)
Hlavní autoři: Fujibayashi, Yuto, Isa, Reiko, Nishiyama, Daichi, Sakamoto-Inada, Natsumi, Kawasumi, Norichika, Yamaguchi, Junko, Kuwahara-Ota, Saeko, Matsumura-Kimoto, Yayoi, Tsukamoto, Taku, Chinen, Yoshiaki, Shimura, Yuji, Kobayashi, Tsutomu, Horiike, Shigeo, Taniwaki, Masafumi, Handa, Hiroshi, Kuroda, Junya
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7464435/
https://ncbi.nlm.nih.gov/pubmed/32781708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12082206
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