Aberrant BUB1 Overexpression Promotes Mitotic Segregation Errors and Chromosomal Instability in Multiple Myeloma

Chromosome instability (CIN), the hallmarks of cancer, reflects ongoing chromosomal changes caused by chromosome segregation errors and results in whole chromosomal or segmental aneuploidy. In multiple myeloma (MM), CIN contributes to the acquisition of tumor heterogeneity, and thereby, to disease p...

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Publicat a:Cancers (Basel)
Autors principals: Fujibayashi, Yuto, Isa, Reiko, Nishiyama, Daichi, Sakamoto-Inada, Natsumi, Kawasumi, Norichika, Yamaguchi, Junko, Kuwahara-Ota, Saeko, Matsumura-Kimoto, Yayoi, Tsukamoto, Taku, Chinen, Yoshiaki, Shimura, Yuji, Kobayashi, Tsutomu, Horiike, Shigeo, Taniwaki, Masafumi, Handa, Hiroshi, Kuroda, Junya
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7464435/
https://ncbi.nlm.nih.gov/pubmed/32781708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12082206
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