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Transient receptor potential cation channels and calcium dyshomeostasis in a mouse model relevant to Malignant Hyperthermia

BACKGROUND: Until recently, the mechanism for the malignant hyperthermia crisis has been attributed solely to sustained massive Ca(2+) release from the sarcoplasmic reticulum on exposure to triggering agents. We now test the hypothesis that transient receptor potential cation (TRPC) channels are imp...

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Foilsithe in:Anesthesiology
Main Authors: Lopez, Jose Rafael, Kaura, Vikas, Hopkins, Phillip, Liu, Xiaochen, Uryach, Arkady, Adams, Jose, Allen, Paul D
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7367496/
https://ncbi.nlm.nih.gov/pubmed/32665491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0000000000003387
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