An Erg11 lanosterol 14-α-demethylase-Arv1 complex is required for Candida albicans virulence

Azole resistant fungal infections remain a health problem for the immune compromised. Current therapies are limited due to rises in new resistance mechanisms. Therefore, it is important to identify new drug targets for drug discovery and novel therapeutics. Arv1 (are1 are2 required for viability 1)...

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Veröffentlicht in:PLoS One
Hauptverfasser: Villasmil, Michelle L., Barbosa, Antonio Daniel, Cunningham, Jessie Lee, Siniossoglou, Symeon, Nickels, Joseph T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2020
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7367482/
https://ncbi.nlm.nih.gov/pubmed/32678853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0235746
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