Computational insights into fluconazole resistance by the suspected mutations in lanosterol 14α-demethylase (Erg11p) of Candida albicans

Mutations in the ergosterol biosynthesis gene 11 (ERG11) of Candida albicans have been frequently reported in fluconazole-resistant clinical isolates. Exploring the mutations and their effect could provide new insights into the underlying mechanism of fluconazole resistance. Erg11p_Threonine285Alani...

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Publicat a:Mol Biol Res Commun
Autors principals: Prakash, Sagunthala Murugesan Udaya, Nazeer, Yasin, Jayanthi, Sivaraman, Kabir, Mohammad Anaul
Format: Artigo
Idioma:Inglês
Publicat: Shiraz University 2020
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7731972/
https://ncbi.nlm.nih.gov/pubmed/33344662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22099/mbrc.2020.36298.1476
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