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Topical Application of the Antimicrobial Agent Triclosan Induces NLRP3 Inflammasome Activation and Mitochondrial Dysfunction

5-Chloro-2-(2,4-dichlorophenoxy)phenol (triclosan) is an antimicrobial chemical widely used in consumer household and clinical healthcare products. Human and animal studies have associated triclosan exposure with allergic disease. Mechanistic studies have identified triclosan as a mitochondrial unco...

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Bibliografiske detaljer
Udgivet i:Toxicol Sci
Main Authors: Weatherly, Lisa M., Shane, Hillary L., Friend, Sherri A., Lukomska, Ewa, Baur, Rachel, Anderson, Stacey E.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7367438/
https://ncbi.nlm.nih.gov/pubmed/32321163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfaa056
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