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Topical Application of the Antimicrobial Agent Triclosan Induces NLRP3 Inflammasome Activation and Mitochondrial Dysfunction

5-Chloro-2-(2,4-dichlorophenoxy)phenol (triclosan) is an antimicrobial chemical widely used in consumer household and clinical healthcare products. Human and animal studies have associated triclosan exposure with allergic disease. Mechanistic studies have identified triclosan as a mitochondrial unco...

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Vydáno v:Toxicol Sci
Hlavní autoři: Weatherly, Lisa M., Shane, Hillary L., Friend, Sherri A., Lukomska, Ewa, Baur, Rachel, Anderson, Stacey E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7367438/
https://ncbi.nlm.nih.gov/pubmed/32321163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfaa056
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