Neurotoxicity of bupivacaine and liposome bupivacaine after sciatic nerve block in healthy and streptozotocin-induced diabetic mice

BACKGROUND: Long-acting local anaesthetics (e.g. bupivacaine hydrochloride) or sustained-release formulations of bupivacaine (e.g. liposomal bupivacaine) may be neurotoxic when applied in the setting of diabetic neuropathy. The aim of the study was to assess neurotoxicity of bupivacaine and liposome...

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Pubblicato in:BMC Vet Res
Autori principali: Markova, Liljana, Umek, Nejc, Horvat, Simon, Hadžić, Admir, Kuroda, Max, Pintarič, Tatjana Stopar, Mrak, Vesna, Cvetko, Erika
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7367396/
https://ncbi.nlm.nih.gov/pubmed/32680505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12917-020-02459-4
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